Gastrodin Injection
Gastrodin Injection

[Indications] For neurasthenia, neurasthenic syndrome and vascular headache disorders (such as migraine, trigeminal neuralgia, occipital bone neuralgia etc.) can also be used for traumatic brain injury syndrome, such as vertigo, dizziness, Meniere's disease resistance of traumatic vertigo, sudden deafness, vestibular neuronitis, vertebral basilar artery insufficiency etc..

[Name of drug]
Gastrodin Injection

Chinese Name: 天麻素注射液

Chinese Pinyin: Tianmasu Zhusheye

 

[Ingredients] Amikacin sulfate

Chemical name: 4- hydroxymethyl benzene -β -D- glucoside.

Chemical formula:

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Molecular formula: C13H18O7·12 H2O

Molecular weight: 295.38

All auxiliary components: None.

[Character] This product is a colorless and transparent liquid.

[Indications] For neurasthenia, neurasthenic syndrome and vascular headache disorders (such as migraine, trigeminal neuralgia, occipital bone neuralgia etc.) can also be used for traumatic brain injury syndrome, such as vertigo, dizziness, Meniere's disease resistance of traumatic vertigo, sudden deafness, vestibular neurons inflammation, Vertebrobasilar arterial insufficiency.

[Specification] 2ml:0.2g

[Usage and Dosage] Intramuscular injection, a 0.1g ~ 0.2g (half to 1), 1 to 2 times a day. Organic diseases can be increased by dosage or as directed by doctors.

[Adverse Effects] A small number of patients had symptoms of dry mouth, dizziness, and stomach upset, but did not affect the patient's acceptance of the medication and did not require special treatment.

[Contraindicated] Anyone who is allergic to this product is prohibited.

[Matters Needing Attention] Prohibit the use of drugs when changes in their properties occur.

 

[Medication for pregnant women and lactating women] Unclear

[Child Medication] The experiment was not conducted and there was no reliable reference.

[Senile Medication] The experiment was not conducted and there was no reliable reference.

[Drug Interactions] The experiment was not conducted and there was no reliable reference.

[Overdose] The experiment was not conducted and there was no reliable reference.

[Pharmacology and Toxicology]

1. Pharmacological: pharmacological test table, tomorrow can restore the cerebral cortex excitatory and inhibitory process between the balance of imbalance, resulting in sedation, sleep and analgesia and other central inhibitory effect.
2. Toxicity: acute toxicity test: mice were injected with oral or caudal vein gastrodin, the dose was used in 5g/kg, observation 3 days, no poisoning and death.
Subacute toxicity test: after 4~6 days, dogs and mice had no effect on red blood cell, white blood cell and platelet count by blood test. Blood test showed no effect on alanine aminotransferase, non protein nitrogen and cholesterol. The heart, lung, spleen, liver, kidney, stomach and intestine of the animals were examined by histological section. No degeneration of cells was observed. The results showed that gastrodin had no effect on hematopoietic system, liver, kidney function and blood lipid.

 

[Pharmacokinetics] After injection, the concentration of serum was consistent with the time of sedation, and the half-life was 4.44 hours. The distribution of kidney in the body is the highest, followed by the liver, lungs, heart, spleen and brain. Mainly excreted from urine, from urine, feces and bile excreted 76.8% of the total dosage, of which 97% excreted urine, mainly in the first 2 hours, bile and feces excreted very little.

 

[Storage] Sealed and stored at room temperature.

[Packing] Ampoule, 10 pcs /  boxes

[Validity]  36 months

[Implementation Criteria] WS1-XG-023-2001

[Approval Number] SFDA approval number H33022310

[Production Enterprise]

Name of enterprise: Zhejiang Chengyi Pharmaceutical Co., Ltd

Production address: No. 118, Chemical Road, Dongtou District, Wenzhou city,Zhejiang province,China

Phone number: 86-577-6348-3979

Fax number: 86-577-6348-5135

URL:http://en.chengyipharma.com

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