Citicoline Sodium Injection
Citicoline Sodium Injection

[Indications] Coenzyme for acute brain injury and postoperative brain disorders.

[Name of drug]
Generic name: Citicoline Sodium Injection
Chinese Name:
胞磷胆碱钠注射液

Chinese Pinyin: Baolindanjianna Zhusheye

[Ingredients]
Main ingredients: citicoline sodium
Chemical name: choline cytosine nucleoside two phosphate monosodium salt.

Structural formula:

     8.jpg

Molecular formula: C14H25N4NaO11P2
Molecular weight: 510.31
All auxiliary components: none.

[Character]  Colorless transparent liquid.
[Indications] Coenzyme for acute brain injury and postoperative brain disorders.
[Specification] 2ml:0.25g

[Usage and Dosage] Intravenous drip: 0.25 to 0.5g (1~2 pieces) a day, with 5% or 10% Glucose Injection diluted slowly drip, every 5~10 days for a course of treatment; intravenous injection: 100 to 200mg every time. Intramuscular injection: 0.1 to 0.3g a day, divided into 1~2 injections.

[Adverse Effects] This product of human and animal had no obvious toxicity, no influence on respiration, pulse and blood pressure, with a drop in blood pressure, insomnia, excitement and drug fever, after stopping drug can disappear.
[contraindication]
The experiment was not carried out and there was no reliable reference.
[Matters Needing Attention] The acute stage of intracerebral hemorrhage should not be used in large doses. Intramuscular injection is generally not used, if used, should always change the injection site.
[pregnant women and lactating women] did not carry out the experiment, and there was no reliable reference.

 

[Medication for Pregnant Women and Lactating Women] The experiment was not conducted and there was no reference.

[Child Medication] The experiment was not conducted and there was no reference.

[Senile Medication] The experiment was not conducted and there was no reference.

[Drug Interactions] The experiment was not conducted and there was no reference.

[Overdose] The experiment was not conducted and there was no reference.

 

[Pharmacology and Toxicology]

This product is a nucleoside derivative that promotes brain metabolism and improves brain circulation by reducing cerebral vascular resistance and increasing brain blood flow. In addition, it can enhance the function of the reticular activating system of the brain stem reticular formation, strengthen the function of the pyramidal system and improve the motor paralysis, so it can promote the recovery of the brain function and promote the revival of the brain.

 

[Pharmacokinetics]

Injection of this product rapidly enters the bloodstream and partly passes through the blood-brain barrier into the brain tissue. Among them, the choline portion becomes a good methylated donor in vivo, which can transfer methylation to a variety of compounds, and approximately 1% of choline can be excreted from urine.

 

[Storage] Shading and airtight preservation.

[Packing] Ampoule packing, 10 pieces / box.

[Validity]  36 months

[Implementation Criteria] Chinese Pharmacopoeia, 2010 edition, two parts

[Approval Number] SFDA approval number  H19999550

 

[Production Enterprise]
Name of enterprise:  Zhejiang Chengyi Pharmaceutical Co., Ltd.
Production address: No. 118, Chemical Road, Dongtou District, Wenzhou city,Zhejiang province,China

Phone number: 86-577-6348-3979

Fax number: 86-577-6348-5135

URL:http://en.chengyipharma.com

If you have any question, please contact us
Our specialist will go one-on-one solutions for you!