- 2024,04,27
With the continuous deepening of research on aminosugars in the pharmaceutical industry, their role is also well-known to more people, and they are also widely used in the improvement and maintenance of bone and joint diseases. Aminosugars are believed to restore proteoglycans from damaged joints and reduce the incidence of osteoarthritis. However, during the process of supplementing with ammonia sugar, there are still some people who have the following doubts:
That's the brand of sulfuric acid or hydrochloric acid glucosamine capsules, how should we choose?
Friends who may be familiar with aminosugars know that they are mainly divided into two types: sulfated glucosamine and hydrochloride glucosamine. In fact, the content of these two types of glucosamine varies, but their biological effects are similar.
The main reason is that the therapeutic effect of glucosamine on osteoarthritis is mainly related to the amount of glucosamine that has been decomposed with the carrier and can be absorbed, and is not related to acid radicals. Glucosamine, which is in a binding state with acid carriers, cannot be absorbed and cannot be bioutilized. Therefore, regardless of the form of glucosamine, as long as it can be decomposed with the carrier in the body and absorbed by the body, its biological effects are similar.
However, glucosamine hydrochloride capsules are safer, more stable, and more effective than glucosamine sulfate capsules!
Research has shown that sulfated sugars are highly hygroscopic and rapidly soluble when exposed to humid environments (ranging from white to stone white to brown to brown), so even imported sulfated sugars are only mixed with sodium sulfate or potassium sulfate on top of sulfated sugars, not just sulfated sugars. After the addition of hydrochloride, the purity of ammonium sulfate can only be maintained at around 80%. On the other hand, aminosugar hydrochloride has a purity of up to 99% due to its good stability.
In addition, good stability and high purity are not sufficient conditions for determining the effect. To achieve better results, the biological activity of true aminosugars, that is, the release amount of active aminosugars, also needs to be considered. Neutral (ionized) aminosugars are truly active substances that are precursors for the body's synthesis of glucosamine, hyaluronic acid, proteoglycans, and collagen, which are precisely what is needed to repair joint cartilage. According to the chemical molecular formulas of aminose sulfate and aminose hydrochloride, it is calculated that aminose hydrochloride can release 83.1% of active aminose, while the release amount of aminose sulfate is 62.8%, indicating that aminose hydrochloride has higher biological activity.
In summary, for friends who need to supplement with glucosamine, it is obviously more appropriate to choose the brand of glucosamine hydrochloride capsules. High quality brands of glucosamine hydrochloride capsules on the market, such as Weigu produced by Chengyi Pharmaceutical, are specific drugs that can prevent, repair, and treat bone and joint diseases. They have been widely used in clinical practice and are highly favored by doctors and patients.
Okay, I'm sure everyone has a clear understanding of the answer to this question. I believe everyone will have a clearer direction when choosing ammonia sugars in their daily lives~
Article source:https://www.bilibili.com/read/cv16816916