- 2024,04,27
The left side is the original needle, and the right side is the plum blossom needle. Provided by Cheng Yi Pharmaceutical
Zhejiang News, January 9th (Shen Quanhui and Kong Jianyi) "If anyone discovers that the injection has a scored head, I will reward them on the spot, with a reward of 1000 yuan each!" Recently, Zeng Fanyun, CEO of Hunan Changsha Chutian Technology Co., Ltd., told colleagues in the pharmaceutical industry who came to inspect. It is understood that the "scorched head" problem of injection is a global problem in the pharmaceutical industry, which still troubles technical personnel in the global pharmaceutical industry and causes significant waste and losses in the production process.
On January 5, 2019, Chutian Science and Technology Park welcomed Yan Yiyi, Chairman of Zhejiang Cheng Yi Pharmaceutical Co., Ltd., and a team of five, to conduct operational acceptance of the "small capacity injection production line" placed in the workshop. This line is an intelligent and automated equipment for the pharmaceutical workshop of Cheng Yi Pharmaceutical's fundraising and technological transformation project.
This acceptance indicates that the "1 milliliter ampoule" produced by Chutian Technology was tested with 10% sugar solution and subjected to strict inspection by Cheng Yi FAT. Zeng Fanyun, who accompanied Cheng Yi Pharmaceuticals for acceptance, appeared confident and offered a "huge reward" on the spot for discovering injection products with a "scored head".
So, all the personnel from Chutian Technology and Cheng Yi Company who participated in the FAT acceptance on site used tools such as white paper to inspect and search, hoping to receive a "reward". However, in the end, no injection product with a "scored head" was found. A burst of enthusiastic applause erupted at the scene! Everyone shook hands with each other and expressed warm congratulations.
"Foreign object scorched head "refers to the phenomenon where the residual liquid from the injection during the filling process gets stuck in the neck wall of the ampoule and is carbonized at high temperature. Especially, aminoglycoside injection products are more prone to producing" scorched head ". Products with" scorched head "are unqualified products and cannot be shipped, which is a global problem in the pharmaceutical industry. For decades, global pharmaceutical companies have started by improving their production processes; Pharmaceutical machinery enterprises have started with the improvement of equipment technology innovation, but have not been able to completely overcome this challenge.
Since using Chutian Technology's second generation linear twelve needle filling and sealing machine in 2013, Cheng Yi Pharmaceutical has achieved a "scored head rate" of over 8.0% for key varieties of small volume injection, such as tolasemide injection, amikacin sulfate injection, and citicoline sodium injection. In recent years, the cumulative losses caused by the "scored head" have exceeded ten million yuan. The impact of 'scorched head' on a pharmaceutical company is like this, and its impact on the global pharmaceutical industry is even more like a 'sword hanging over the head'.
Last year, when Chengyi Pharmaceutical decided to purchase equipment from Chutian Technology, Yan Yiyi proposed using the solution of "scorched head" as the preferred condition for the project, and personally met with Chutian Technology equipment design engineers to participate in the special research meeting of their research group. The solution was proposed: after the equipment was filled, the nitrogen filling needle used the plum blossom needle designed under Yan Yiyi's guidance to blow away the liquid medicine that had adhered to the glass wall, so that the carbonization of the liquid medicine could be completely solved. Chutian Technology has introduced advanced processing equipment from Germany and produced exquisite needle injection products. Therefore, there is the scene where Zeng Fanyun offered a reward on-site at the beginning of this article.
Yan Yiyi has been in the industry for over fifty years, and this time, he led the innovation and launch of the "Filling Plum Blossom Needle", which solved the global problems in the pharmaceutical industry. This is a great joy for Cheng Yi Pharmaceutical and also for the Chinese pharmaceutical industry.